产品货号:
Z24510
中文名称:
PRTFDC1抗体
英文名称:
Anti-PRTFDC1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PRTFDC1 Antibody |
指标别名 | HHGP;PRTFDC1 |
克隆性 | Polyclonal |
检验物种 | human,rat |
应用范围 | ELISA,WB |
基因名称 | PRTFDC1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | PRTFDC1 antibody was raised against a 14 amino acid synthetic peptide from near the center of human PRTFDC1.The immunogen is located within amino acids 90 - 140 of PRTFDC1. |
计算分子量 | 26kDa |
成分 | PRTFDC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | PRTFDC1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene.Recently,it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC),leading to gene silencing.Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays,while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth.These results suggest that PRTFDC1 can act as a tumor-suppressor gene.At least three isoforms of PRTFDC1 are known to exist. |
Uniprot ID | Q9NRG1 |
基因名全称 | Phosphoribosyl transferase domain containing 1 |
蛋白名全称 | Phosphoribosyl transferase domain containing 1 |
推荐稀释比 | PRTFDC1 antibody can be used for detection of PRTFDC1 by Western blot at 1μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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